Mesalazine 400mg (Generic)

What is Mesalazine 400mg?

Mesalazine 400mg is a prescription medication containing Mesalazine as the active ingredient. It belongs to the class of drugs known as aminosalicylates and is primarily used to treat inflammatory bowel conditions. Developed by Sun Pharmaceutical Industries Ltd, this formulation is designed to deliver effective anti-inflammatory action within the gastrointestinal tract.

Mesalazine 400mg is commonly prescribed for patients diagnosed with ulcerative colitis and Crohn’s disease, conditions characterised by inflammation of the digestive tract. Its targeted action helps in reducing the symptoms and maintaining remission to improve patients’ quality of life.

Uses of Mesalazine 400mg

• Treatment of ulcerative colitis
• Managing Crohn’s disease symptoms
• Maintenance therapy to prevent relapse of inflammatory bowel diseases
• Reducing inflammation in the colon and rectum

How Mesalazine 400mg Works

Mesalazine 400mg works by delivering the active compound Mesalazine directly to the lining of the intestines, where inflammation occurs in conditions like ulcerative colitis and Crohn’s disease. It acts locally in the gut to inhibit the production of inflammatory chemicals such as prostaglandins and leukotrienes. By reducing this inflammation, Mesalazine helps to alleviate symptoms such as diarrhoea, abdominal pain, and rectal bleeding. This anti-inflammatory mechanism supports mucosal healing and helps maintain long-term remission.

Benefits of Mesalazine 400mg

• Effectively reduces inflammation in the colon
• Helps maintain remission and prevent flare-ups
• Targets affected areas directly to maximise efficacy
• Relieves symptoms like pain, bleeding, and diarrhoea
• Used as a well-established treatment option in the UK

Dosage and Administration

The recommended dosage of Mesalazine 400mg varies based on the patient’s condition and the severity of symptoms. Typically, the medicine is taken orally, with doses spread evenly throughout the day to maintain steady drug levels. It is important to follow the prescribing healthcare professional’s instructions carefully. Swallow tablets whole with water, and avoid crushing or chewing. Consistency in taking Mesalazine ensures optimal control of inflammation and symptom relief. Other forms, such as Mesalazine 1gm Suppository, Mesacol 800mg and Mesalamine 800 mg, are also listed.

Who Should Use Mesalazine 400mg?

Mesalazine 400mg is intended for patients diagnosed with inflammatory bowel diseases such as ulcerative colitis and Crohn’s disease. It is suitable for those requiring anti-inflammatory treatment to manage symptoms or maintain remission. Patients under medical supervision who have no contraindications for Mesalazine can benefit from this therapy.

Who Should Avoid Mesalazine 400mg?

Patients with known hypersensitivity to Mesalazine or any component of the tablet should avoid use. Those with severe kidney or liver impairment need careful evaluation before treatment. Pregnant or breastfeeding women should consult their doctor prior to taking this medicine. Individuals with blood disorders or certain rare enzyme deficiencies might also be advised against using Mesalazine.

Side Effects

• Headache
• Nausea
• Abdominal pain
• Diarrhoea
• Flatulence
• Dizziness
• Rash or itching
• Fever
• Muscle aches
• Elevated liver enzymes (rare)
• Kidney function changes (rare)

Safety Advice

• Inform your doctor of all medications before starting Mesalazine
• Report any unusual symptoms or allergic reactions immediately
• Regular blood tests may be required to monitor kidney and liver function
• Do not stop treatment abruptly without medical advice
• Take the medication exactly as prescribed to avoid relapse
• Consult your healthcare provider if you become pregnant while using this medicine

Drug Interactions

• Azathioprine or mercaptopurine – increased risk of blood disorders
• Nonsteroidal anti-inflammatory drugs (NSAIDs) – potential increased kidney risk
• Antacids containing magnesium – may reduce Mesalazine absorption
• Sulfasalazine – overlapping effects with Mesalazine

Storage Instructions

Store Mesalazine 400mg tablets at room temperature, away from moisture, heat, and direct light. Keep the medicine in its original packaging and out of the reach of children. Do not use the drug after the expiration date printed on the package.

Where to buy Mesalazine 400mg in UK?

Mesalazine 400mg is available for purchase in licensed pharmacies across the UK and through reputable online pharmacies. It is important to obtain this medication via a valid prescription from a healthcare professional. Buying from authorised sources ensures the product’s authenticity and safety.

Frequently Asked Questions (FAQ)

Is Mesalazine 400mg available in UK?

Yes, Mesalazine 400mg is widely available in the UK upon prescription. It is commonly stocked in community pharmacies and hospital pharmacies.

What is the price of Mesalazine 400mg in UK?

The price can vary depending on the pharmacy and prescription arrangements. It is advisable to check with local pharmacies or online providers for current pricing.

What happens if I miss a dose?

If you miss a dose of Mesalazine 400mg, take it as soon as you remember unless it is close to the time for your next dose. Do not double the dose to catch up.

Where can I find Mesalazine 400mg for sale?

You can find Mesalazine 400mg for sale in licensed UK pharmacies and through verified online pharmacy platforms with a valid prescription.

Can I take Mesalazine 400mg during pregnancy?

Consult your doctor before using Mesalazine during pregnancy. Your healthcare provider will weigh the benefits and risks before prescribing.

Are there any dietary restrictions while on Mesalazine 400mg?

There are no specific dietary restrictions, but maintaining a balanced diet helps overall gut health. Discuss any concerns with your healthcare professional.

How long does it take for Mesalazine 400mg to work?

The effect may begin within a few days to weeks, but full benefits often require consistent use over a longer period. Follow your doctor’s guidance for treatment duration.

Conclusion

Mesalazine 400mg, manufactured by Sun Pharmaceutical Industries Ltd, is a trusted medication for managing ulcerative colitis and Crohn’s disease. Its targeted anti-inflammatory action helps control symptoms, promote healing, and maintain remission. When taken as prescribed, it offers a valuable treatment option for patients seeking relief from inflammatory bowel conditions in the UK.