Mesalazine 1gm Suppository (Generic)

What is Mesalazine 1gm Suppository?

Mesalazine 1gm Suppository is a pharmaceutical formulation designed for rectal administration, containing the active ingredient Mesalazine, which is widely used in the management of inflammatory bowel diseases. Manufactured by Sun Pharmaceutical Industries Ltd, this suppository aims to deliver targeted anti-inflammatory effects directly to the affected areas within the lower bowel, offering a precise approach to treatment.

Primarily prescribed for conditions such as ulcerative colitis and Crohn’s disease, Mesalazine 1gm Suppository helps reduce inflammation and ease symptoms associated with these chronic gastrointestinal disorders. Its localized delivery minimizes systemic exposure, making it a valuable option for patients seeking effective management of distal colitis symptoms.

Uses of Mesalazine 1gm Suppository

• Treatment of ulcerative colitis, particularly proctitis and left-sided colitis
• Management of inflammation in Crohn’s disease affecting the rectal or lower colon region
• Maintenance therapy to prevent relapse in ulcerative colitis
• Relief of symptoms such as rectal bleeding, pain, and urgency

How Mesalazine 1gm Suppository Works

Mesalazine, the active ingredient in this suppository, is an anti-inflammatory agent that acts topically within the colon. It inhibits the production of inflammatory mediators like prostaglandins and leukotrienes, which are responsible for causing inflammation and tissue damage in the bowel lining. By delivering Mesalazine directly to the site of inflammation, the suppository helps suppress the immune response that triggers ulcerative colitis and Crohn’s disease symptoms.

Benefits of Mesalazine 1gm Suppository

• Effective localized treatment for distal colonic inflammation
• Reduces symptoms such as bleeding and abdominal pain
• Minimizes systemic side effects due to targeted delivery
• Supports maintenance of remission in ulcerative colitis patients
• Easy to use with convenient rectal administration

Dosage and Administration

The typical dosage of Mesalazine 1gm Suppository varies depending on the severity of the condition and physician recommendations. Usually, one suppository is administered rectally once or twice daily, preferably after a bowel movement or at bedtime. Patients should insert the suppository gently into the rectum and allow it to dissolve for optimal absorption. Consistent adherence to prescribed dosing is essential for effective symptom management. Other forms, such as Mesalazine 400mg, Mesacol 1gm Suppository and Mesalo Foam, are also listed.

Who Should Use Mesalazine 1gm Suppository?

Mesalazine suppositories are suitable for patients diagnosed with mild to moderate ulcerative colitis affecting the rectum or lower colon and those with localized Crohn’s disease symptoms. It is typically recommended for individuals who require targeted anti-inflammatory therapy and prefer rectal treatment to deliver medication directly to the site of inflammation. Patients should always consult a healthcare professional before starting therapy.

Who Should Avoid Mesalazine 1gm Suppository?

Individuals with a known hypersensitivity or allergy to Mesalazine, sulfasalazine, or any excipients in the suppository should avoid use. It is also not recommended for patients with severe renal or hepatic impairment without medical supervision. Pregnant or breastfeeding women should seek medical advice before considering Mesalazine treatment.

Side Effects

• Rectal irritation or discomfort
• Headache
• Nausea
• Abdominal pain
• Diarrhea
• Rash or skin reactions
• Fever
• Dizziness

Safety Advice

• Consult your doctor before use if you have kidney or liver problems
• Avoid using if allergic to Mesalazine or related compounds
• Do not exceed recommended dosage
• Inform your healthcare provider about all medications you are taking
• Discontinue and seek medical advice if you experience severe side effects
• Store out of reach of children

Drug Interactions

• May interact with other anti-inflammatory drugs
• Potential interaction with blood thinners requiring monitoring
• Concurrent use with immunosuppressants should be supervised by a doctor
• Consult your healthcare provider before combining with other medications

Storage Instructions

Store Mesalazine 1gm Suppository in a cool, dry place away from direct sunlight and moisture. Keep the suppositories in their original packaging until use. Do not freeze. Ensure the medication is stored at a temperature below 25°C to maintain efficacy and shelf life.

Where to buy Mesalazine 1gm Suppository in UK?

Mesalazine 1gm Suppository is available for purchase at licensed pharmacies and reputable online medicine stores throughout the UK. Ensure you are buying from a trusted supplier to guarantee product authenticity and safety. Prescription from a healthcare professional is typically required for purchase.

Frequently Asked Questions (FAQ)

Is Mesalazine 1gm Suppository available in UK?

Yes, Mesalazine 1gm Suppository is available in the UK and can be obtained with a valid prescription from licensed pharmacies and authorized online vendors.

What is the price of Mesalazine 1gm Suppository in UK?

The price of Mesalazine 1gm Suppository in the UK varies depending on the pharmacy and insurance coverage. It is advisable to consult your local pharmacy or online retailer for current pricing details.

What happens if I miss a dose?

If you miss a dose of Mesalazine 1gm Suppository, take it as soon as you remember unless it is close to the time for your next dose. Do not double the dose to make up for a missed one.

Where can I find Mesalazine 1gm Suppository for sale?

You can find Mesalazine 1gm Suppository for sale at accredited pharmacies across the UK or from reputable online pharmaceutical suppliers. Always ensure the seller is legitimate and requires a prescription.

Can I use Mesalazine suppositories during pregnancy?

Pregnant women should consult their healthcare provider before using Mesalazine 1gm Suppository to understand the benefits and potential risks involved.

How long does it take for Mesalazine suppositories to work?

Patients may begin to notice symptom relief within a few days of regular use, but it can take several weeks for full therapeutic effects. Always follow your doctor’s guidance regarding treatment duration.

Are there any dietary restrictions while using Mesalazine?

There are no specific dietary restrictions associated with Mesalazine 1gm Suppository, but maintaining a balanced diet can support overall gut health during treatment.

Conclusion

Mesalazine 1gm Suppository offers an effective and targeted treatment option for managing ulcerative colitis and Crohn’s disease symptoms, particularly affecting the rectal and lower colon region. Developed by Sun Pharmaceutical Industries Ltd, its local anti-inflammatory action helps reduce inflammation and maintain remission with fewer systemic side effects. Suitable for patients requiring precision therapy, this suppository is a trusted choice in the UK for those seeking relief from inflammatory bowel conditions under professional healthcare guidance.