Ismo Retard 40 Mg (Isosorbide Mononitrate)

Overview of Ismo Retard 40 Mg

Ismo Retard 40 mg tablet (Isosorbide Mononitrate) is mainly prescribed among patients experiencing heart-related chest pain (angina). Although effective in controlling and managing symptoms of angina, it cannot treat an angina attack already begun. It is thus recommended to get appropriate medical guidance before starting treatment with this drug.

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What is Ismo Retard 40 Mg?

Ismo Retard 40 is an oral tablet prescribed for preventing chest pain related to heart conditions (medically termed angina). It contains Isosorbide Mononitrate as the main ingredient which works by relaxing and broadening blood vessels so that blood flow remains smooth towards the heart.

This medicine delivers desired health improvements when used as advised and paired with lifestyle changes (regular exercise, diet, and quitting alcohol/smoking).

Note: When used for a longer period, the patient’s body may develop resistance to the dosage strength. Hence, dosage adjustment is required.

How Ismo Retard 40 Mg Works?

Isosorbide Mononitrate, the main ingredient of this medicine belongs to the class of drugs called nitrate vasodilators.

Once administered, this ingredient converts into free radical nitric oxide in the body which activates guanylate cyclase enzymes in turn. Next, cyclic GMP synthesis happens in the smooth muscles and tissues causing dephosphorylation of the smooth muscles. Thus, relaxation is promoted while blood flow increases in veins, arteries, and cardiovascular tissues. Consequently, the workload of cardiac muscles reduces while relieving symptoms of angina.

Uses of Ismo Retard 40 Mg

• Preventing Angina (Heart-related chest pain)

Dosage and Administration

Use Ismo Retard 40mg tablets as indicated by the physician. It is mostly a long-term treatment with one tablet used at a fixed time daily. Patients should remain consistent with their treatment schedule to avail expected benefits of the treatment with this medicine.

Swallow one whole Isosorbide Mononitrate pill with a glass of water with or without food. In case you experience nausea or vomiting, try taking your further dosages with/right after a simple meal.

Don’t divide, chew, or crush the tablet else it can become less effective.

The patient needs to avoid smoking or alcohol throughout the treatment period to ensure the desired efficacy of the medicine.

Don’t modify the treatment plan by using this medicine in more or less amounts/frequency than advised by the physician.

Benefits of Ismo Retard 40 Mg

• Effectively prevents symptoms of angina
• Promotes heart health and overall wellness
• Fewer manageable side effects only
• Provides long-lasting relief
• Improves exercise tolerance
• Prevents the risk of heart attacks
• Lowers blood pressure while benefitting cardiac health

Potential Side Effects

Any of these common side effects could occur during the treatment period. Don’t reach for medical aid promptly unless they are severe such as increased chest pain, fainting, collapse, etc. Below are the side effects settling by themselves in no time as the body adjusts with Isosorbide Mononitrate.

• Nausea
• Low blood pressure
• Headache
• Vomiting
• Blood pressure drops while standing up
• Increased heartbeat
• Weakness
• Dizziness

How to Manage Side Effects?

Common side effects like nausea and vomiting can be managed by sticking to simple meals and avoiding spicy foods. It is also important to avoid using the dosage on an empty stomach. For managing headaches, drink a lot of fluids while avoiding alcohol.

Interactions with Other Medications

Inform your healthcare provider if you’re taking any of these commonly interacting drugs of Ismo Retard 40 tablets:

• Riociguat
• ACE-inhibitor drugs used for treating high blood pressure
• Erectile dysfunction medicines
• Any medicines containing long-acting nitrates (substitute medicines for angina)
• Psychotic disorder medications
• Migraine medicines
• Tricyclic antidepressants
• Cancer treatments
• Medicines lowering phenylalanine levels in blood

Precautions and Warnings

• This drug is not suitable for pregnant and breastfeeding women. Inform the healthcare professional before taking the same during such medical conditions.
• Don’t attempt any kind of attention-needing activities right after the dosage.
• It may not be advised among patients with kidney or liver impairments.
• Ensure you’re not allergic to isosorbide-5-mononitrate before buying/using this medicine.
• Inform your healthcare professional in case you have any other heart health complications.
• Share your medical history with the doctor for appropriate guidance.

Proper Storage Conditions

• Ensure appropriate storage for longer shelf-life and undamaged medicine quality. Keep it below 25 Degrees Celsius.
• Place it out of reach of children and pets.

FAQs

What should I do if I miss a dose?

If you have missed out on taking the dosage timely, take it as you remember only if your next dose is not scheduled soon. Do not catch up with missed doses by taking two tablets during the next dosage.

Can Ismo Retard 40 Mg be taken with food?

It can be taken with or without food. However, it is mostly suggested to use it with or right after a simple meal to prevent nausea or vomiting. Avoid eating spicy foods while on treatment with this drug.

How long does it take to see results?

This extended-release isosorbide-5- mononitrate tablet works within 30 minutes of dosage while remaining effective for up to 17 hours.

Is Ismo Retard 40 Mg suitable for everyone?

Ismo may not suit patients with pre-existing medical conditions like anaemia, dialysis (kidney failure), hypotension (high blood pressure), glaucoma (increased eye pressure), etc. Such patients should share their medical history with the healthcare professional while being prescribed this drug.

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