Pirfenidone 801 mg (Generic)

What is Pirfenidone 801 mg?

Pirfenidone 801 mg is a prescription medication used primarily in the management of idiopathic pulmonary fibrosis (IPF), a chronic and progressive lung disease. Manufactured by Cipla Limited, this pharmaceutical formulation contains the active ingredient Pirfenidone, which has antifibrotic and anti-inflammatory properties that help slow the decline in lung function associated with IPF.

In the UK, Pirfenidone 801 mg offers an important treatment option for patients diagnosed with this condition, aiming to improve their quality of life and manage symptoms effectively. It is commonly prescribed following specialist consultation and diagnosis.

Uses of Pirfenidone 801 mg

• Treatment of idiopathic pulmonary fibrosis (IPF)
• Slowing the progression of lung fibrosis
• Reducing lung inflammation
• Improving respiratory function and symptom management in IPF patients

How Pirfenidone 801 mg Works

Pirfenidone works by inhibiting the synthesis of collagen, a key component in fibrotic tissue formation within the lungs. By suppressing the activities of transforming growth factor-beta (TGF-β) and other cytokines involved in inflammation and fibrosis, Pirfenidone helps reduce the scarring process that impairs lung function in IPF patients.

This mechanism of action makes Pirfenidone 801 mg an effective antifibrotic agent that supports slowing disease progression in the lungs and potentially preserving lung capacity over time.

Benefits of Pirfenidone 801 mg

• Slows the progression of idiopathic pulmonary fibrosis
• Reduces lung inflammation and fibrosis
• Helps maintain lung function longer
• May improve symptoms such as breathlessness and cough
• Orally administered and convenient to use

Dosage and Administration

Pirfenidone 801 mg tablets should be taken orally with water, preferably during or after meals to minimize gastrointestinal discomfort. The recommended dose and titration schedule should be strictly followed as advised by a healthcare professional. Typically, dosing starts with a lower amount and is gradually increased to the full dose of 801 mg three times daily.

Patients must not alter the dose without consulting their doctor. Consistency and adherence to the prescribed regimen are vital for effective treatment.

Who Should Use Pirfenidone 801 mg?

Pirfenidone 801 mg is intended for adults diagnosed with idiopathic pulmonary fibrosis. It is prescribed after thorough medical evaluation and confirmation of IPF through clinical and radiological assessments. This medication is suitable for patients in stages of the disease where slowing progression of fibrosis can provide clinical benefit.

Who Should Avoid Pirfenidone 801 mg?

Individuals with hypersensitivity to Pirfenidone or any excipients in the tablet should avoid this medication. It is also contraindicated in patients with severe liver or kidney impairment. Women who are pregnant or breastfeeding should not use Pirfenidone without medical advice. Caution is advised in patients with a history of phototoxic reactions or severe skin disorders.

Side Effects

• Nausea
• Diarrhea
• Fatigue
• Dizziness
• Skin rash
• Photosensitivity reactions
• Indigestion
• Headache
• Loss of appetite
• Elevated liver enzymes

Safety Advice

• Take the medication exactly as prescribed by your healthcare provider
• Avoid excessive sun exposure and use protective clothing and sunscreen due to photosensitivity risk
• Report any unusual symptoms or side effects promptly to your doctor
• Regularly monitor liver function tests during treatment
• Do not discontinue treatment abruptly without consultation
• Inform your healthcare provider about all other medications you are taking to avoid interactions

Drug Interactions

• Strong CYP1A2 inhibitors may increase Pirfenidone levels
• Co-administration with fluvoxamine is not recommended
• Smoking can reduce effectiveness by increasing metabolism
• Check with your doctor before taking other prescription or over-the-counter drugs

Storage Instructions

Store Pirfenidone 801 mg tablets in a cool, dry place away from direct sunlight and moisture. Keep out of reach of children. The medication should be stored at room temperature, typically between 20°C to 25°C (68°F to 77°F). Do not use the product past its expiration date.

Where to buy Pirfenidone 801 mg in UK?

In the UK, Pirfenidone 801 mg can be obtained with a prescription from licensed pharmacies. It is important to purchase this medication from reputable sources to ensure authenticity and safety. Several licensed online pharmacies also supply Pirfenidone 801 mg, maintaining compliance with UK regulations and standards. Always consult your healthcare provider before buying and using this medication.

Frequently Asked Questions (FAQ)

Is Pirfenidone 801 mg available in UK?

Yes, Pirfenidone 801 mg is available in the UK through licensed pharmacies with a valid prescription.

What is the price of Pirfenidone 801 mg in UK?

The price of Pirfenidone 801 mg varies depending on the pharmacy and prescription coverage. It is advisable to consult your healthcare provider or pharmacy for current pricing details.

What happens if I miss a dose?

If you miss a dose, take it as soon as you remember unless it is almost time for your next dose. Do not double doses to make up for a missed one. Consult your doctor if you are unsure.

Where can I find Pirfenidone 801 mg for sale?

You can find Pirfenidone 801 mg in UK licensed pharmacies and reputable online medicine providers that comply with local regulations.

Can I take Pirfenidone 801 mg with other medications?

Some medications may interact with Pirfenidone. Always inform your doctor about any other medicines, supplements, or herbal products you are using.

Are there dietary restrictions while taking Pirfenidone 801 mg?

It is recommended to take Pirfenidone with food to reduce stomach upset. Avoid excessive alcohol consumption and smoking during treatment for optimal results.

How long does it take for Pirfenidone 801 mg to work?

The effects of Pirfenidone in slowing lung function decline are usually seen with continuous use over several months. Regular follow-up with your healthcare provider is important to assess treatment response.

Conclusion

Pirfenidone 801 mg is a significant treatment option for patients with idiopathic pulmonary fibrosis in the UK, offering the potential to slow the disease progression and manage symptoms effectively. Manufactured by Cipla Limited, this medication works through its antifibrotic and anti-inflammatory properties, contributing to better lung health over time. Proper use under medical supervision, adherence to dosage guidelines, and awareness of potential side effects ensure safe and effective therapy for those affected by IPF.